Methods: This study is a cross-sectional study, analyze the records of patients’ chart, who were come from a medical center in central Taiwan for checkup the coronary artery stenosis and calcification. The records of 438 checkup patients who also do a 640 multi-detector-row computed tomography examination were collected and estimated by two cardiovascular disease risk assessment tools: The Framingham Coronary Heart Disease Risk Score, version 2008 (FCHDRS 2008) and the Pooled Cohort Equations 10-year Atherosclerotic Cardiovascular Disease (ASCVD) Risk Estimator. And then, the data were categorized into three groups: (1) patients with stenosis of one coronary artery blood vessel≧50%, (2) patients with coronary artery calcification ≧400, and (3) patients with either stenosis of one coronary artery blood vessel≧50% or coronary artery calcification≧400 and analyzed with logistic regression and Receiver Operating Characteristic curve (ROC curve) methods.
Results: There are 100 (22.8%) participants in 438 with artery stenosis≧50%, and 75(17.1%) with calcification≧100 score. The risk assessment by FCHDR 2008 are as follow: 213(49.2%) participants have low-middle risk, 129 (29.7%) participants have middle risk, and 92(21.1%) participants have high risk. While the risk assessment by ASCVD are: 266(60.7%) have middle risk, and 169(38.6%) have high risk. Male are more prone to coronary artery stenosis calcification than female. Both logistic regression analysis and the ROC curve analysis show the 10-year ASCVD Risk Estimator has a higher correlation with all the three groups than Framinghan risk scores ( logistic regression analysis: P<0.000,OR=1.06,95%CI=1.00-1.12; ROC analysis: AUC = 0.709).
Conclusion: Pooled Cohort Equations 10-year ASCVD Risk Estimator is the most effective risk assessment tool to predict coronary artery disease risks for people in Taiwan.
See more of: Oral Paper & Poster: Science Sessions