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Sunday, November 1, 2009
Learning Objective 1: describe the factors making under-representation of African-Americans in cancer clinical trials a cancer disparity
Learning Objective 2: discuss the applicability of the PRECEDE-PROCEED framework for designing, implementing, and evaluating interventions for recruitment and accrual of African-American cancer patients in cancer clinical trials.
Under-representation of African Americans in Cancer Clinical Trials
Terease S. Waite, RN, BSN, JD
University of Pennsylvania School of Nursing
Significance: As defined by the National Institutes of Health, a cancer disparity represents adverse differences in cancer incidence, prevalence, mortality, survival burden, or other health-related conditions. For the years 1974 through 2003, the Surveillance, Epidemiology, and End Results Programs (SEER) indicated that, though a minority population in the U.S., African Americans outpace Caucasians in cancer incidence and cancer mortality, while lagging in cancer survival. The significant under-representation of African American cancer patients in cancer clinical trials is a little recognized, but serious public health problem. Because cancer clinical trials improve therapeutic outcomes, advance treatment, and promote prevention, progress in the treatment of cancer and reduction of cancer disparities in African Americans is best accomplished by recruitment and accrual of more African Americans in cancer clinical trials.
Purpose/Aim: The aim of this poster presentation is to (1) discuss the applicability of the PRECEDE-PROCEED framework for designing, implementing, and evaluating proposed interventions for reducing cancer disparity by increasing recruitment and accrual of African American cancer patients in cancer clinical trials and (2) outline a proposed, combined qualitative/quantitative research design for execution of Phase I of the PRECEDE-PROCEED framework.
Methods: Visual presentation of (1) the PRECEDE-PROCEED framework as applied to reduction of cancer disparity in African Americans, (2) a proposed qualitative/quantitative research design to be used in Phase I of the PRECEDE-PROCEED framework.
Results/Conclusions and Implications: The Precede-Proceed framework is a comprehensive methodology useful in planning, designing, implementing, and evaluating research targeting recruitment and accrual of African American cancer patients in cancer clinical trials. Its multi-factorial analysis facilitates reduction of cancer disparity at the individual and community level.
Terease S. Waite, RN, BSN, JD
University of Pennsylvania School of Nursing
Significance: As defined by the National Institutes of Health, a cancer disparity represents adverse differences in cancer incidence, prevalence, mortality, survival burden, or other health-related conditions. For the years 1974 through 2003, the Surveillance, Epidemiology, and End Results Programs (SEER) indicated that, though a minority population in the U.S., African Americans outpace Caucasians in cancer incidence and cancer mortality, while lagging in cancer survival. The significant under-representation of African American cancer patients in cancer clinical trials is a little recognized, but serious public health problem. Because cancer clinical trials improve therapeutic outcomes, advance treatment, and promote prevention, progress in the treatment of cancer and reduction of cancer disparities in African Americans is best accomplished by recruitment and accrual of more African Americans in cancer clinical trials.
Purpose/Aim: The aim of this poster presentation is to (1) discuss the applicability of the PRECEDE-PROCEED framework for designing, implementing, and evaluating proposed interventions for reducing cancer disparity by increasing recruitment and accrual of African American cancer patients in cancer clinical trials and (2) outline a proposed, combined qualitative/quantitative research design for execution of Phase I of the PRECEDE-PROCEED framework.
Methods: Visual presentation of (1) the PRECEDE-PROCEED framework as applied to reduction of cancer disparity in African Americans, (2) a proposed qualitative/quantitative research design to be used in Phase I of the PRECEDE-PROCEED framework.
Results/Conclusions and Implications: The Precede-Proceed framework is a comprehensive methodology useful in planning, designing, implementing, and evaluating research targeting recruitment and accrual of African American cancer patients in cancer clinical trials. Its multi-factorial analysis facilitates reduction of cancer disparity at the individual and community level.