Learning Objective 1: discuss the association between ventilator associated pneumonia and NG feeding
Learning Objective 2: discuss the effects of different methods of NG feeding on pulmonary aspiration and on gastric empty
A broad computerized literature search was conducted using both Chinese and English databases, as well as the reference lists of relevant articles. Articles that met selection criteria were carefully examined by two reviewers to make a final selection of the studies for this review. A total of seven studies were included in this comprehensive meta-analysis. Data were extracted and collected independently by the two reviewers and cross-checked. Comprehensive Meta-analysis version 2 (Biostate, 2006) was used to analysis statistical data extracted from retrieved articles and to conduct meta-analysis.
There were no definitive studies showing either intermittent or continuous NG feeding is better in the outcomes of gastric emptying or the amount of lipid-laden macrophage presented in sputum. However, the result showed intermittent NG feeding is better than continuous NG feeding in terms of less neutrophils present in sputum. Nevertheless, the current strength of evidence is weak and well-designed studies are strongly recommended. Based on the current evidence, it is not possible to state that one NG feeding method is better than the other.