Monday, November 3, 2003

This presentation is part of : Research Development

Hepatitis C: A Program of Research

Donna Zucker, RN, PhD, University of Massachusetts, Amherst, MA, USA
Learning Objective #1: Discuss the significance of hepatitis C research relative to the public's health
Learning Objective #2: Understand the importance of biobehavioral factors that influence the trajectory of the disease

Hepatitis C: A Program of Research Objective: The objective of this paper is to present a 5 year research trajectory of hepatitis C research. Design: This paper describes a series of studies utilizing secondary analysis, focus group research, case study and randomized clinical trial data. Population, Sample, Setting : In each case the population includes persons with chronic hepatitis C from the northeastern portion of this country. The samples range in size: 1 case study, 3 focus groups, 50 patients and 20 clinical trail subjects. Study subjects include women only, both gender and incarcerated females. Concept or Variables Studied Together : The major concepts studied are adverse events to combination therapy, symptom cluster, and adherence. Methods: Methods for each study design include in-depth interviews, chart review, and two-group design. Findings: Findings suggest the need for biobehavioral interventions to prevent the spread of this virus. These include education, behavior modification and support tailored to specific group needs. Conclusions : Results from these combined studies suggest the imperative to educate the public as well as patients with hepatitis C. Needle exchange legislation is a long-term goal for eradication of this virus. Implications: More information is needed about the complex needs of hepatitis C patients of various minority and cultural backgrounds. Current data demonstrates a large health disparity in extending hepatitis C treatment to minorities and the incarcerated.

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