Learning Objective 1: compare the four different eGFR equations and understand the CKD staging.
Learning Objective 2: find out the link between metabolic characteristics and urinary abnmormalities of the stage 3~5 CKD subjects
Method: A prospective, cross-sectional, community-based study was conducted in Chiayi City from April to August 2007. Eligible subjects age 30 years or over and native to Chiayi City were submitted biochemical profiles and urinalysis by dipstick. CKD stage 3-5 subjects were further studied using the four eGFR equations.
Results: Among the 1360 study subjects (male 38.3%), mean age was 56.05±11.67 year-old, creatinine 0.84±0.23 mg/dL, Comparing metabolic disturbance of CKD stage 3-5 subjects by eGFR equations, there were significant differences among the four groups: CCR(MDRD-USA) found a higher ratio of: 1) female waist circumference³80cm, 2) total cholesterol ³200mg/dL, 3) triglyceride³150mg/dL, and 4) body mass index³22 kg/m2. In CCR(MDRD-USA) group (n=21), 33.3% having urine protein³1+ compared to CCR(MDRD-China) (n=57) 24.6%, CCR(MDRD-Japan) (n=527) 7.4% and CCR(CCG) group (n=160) 16.3% was statistically significant (p< 0.01).
Conclusion:CCR(MDRD-USA) with dipstick can be an efficient screening tool for identifying CKD stage 3-5 subjects in a community-based multiple screening program.
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