Learning Objective 1: The learner will be able to understand the differences in estradiol and IL-8 between women with hyperemesis gravidarum and mild nausea and vomiting during pregnancy.
Learning Objective 2: The learner will be able to understand the knowledge of birth outcomes between women with hyperemesis gravidarum and mild nausea and vomiting during pregnancy.
Methods: To examine the hCG, estradiol, and IL-8, every pregnant woman was collected the biochemical data follow her prenatal clinical routine. In addition, two measurement instruments were used in this study: the Demographic Inventory (DI), and the Index of Nausea, Vomiting, and Retching (INVR). Data were analyzed using SPSS packages for Windows, including descriptive statistics, independent-samples t test, and χ2 test.
Results: A total of 102 pregnant women were recruited in this study and divided into two groups: HG (40 subjects) and mild NV (62 subjects) groups. The average age of these participants was 30.86±3.61 years. Most women (43.2%) were educated at undergraduate level, most (79.7%) were employed, and 46.1% were primigravida. The results of independent-samples t test showed that women with HG (20.50±2.16) had significantly lower body mass index than women with mild NV (22.04±2.86) (p = .006). A χ2 test indicated that women with HG had significantly higher ratio of birth complications than mild NV (p = .029). The levels of hCG (95.38x103±42.73x103 vs. 99.93x103±43.74x103), estradiol (13.48x102±13.40x102 vs. 12.70x102±12.24x102) and IL8 (36.01±33.58 vs. 51.08±49.34) for the two groups were different but not significant. The birth weights (3.04±.44 vs. 2.97±
Conclusion: The findings of this study provided an advanced understanding of the knowledge relative to hCG, estradiol, IL-8, and birth outcomes between women with HG and mild NV during pregnancy.
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