The Relationship Between Illness Uncertainty, Social Support and Depression in Patients with Cholangiocarcinoma

Wednesday, 24 July 2013

Chiao Ying Chen, MS, RN
Department of Nursing, Chang Gung Memerial Hospital at Linkou, Taoyuan, Taiwan

Learning Objective 1: This study provide clinical staff understand the cholangiocarcinoma and its influencing factors in patients with depression.

Learning Objective 2: Important explanatory factor of cholangiocarcinoma in patients with depression as adisease and symptom distress, uncertainty.

Purpose: The purpose of this study was to explore the relationship of uncertainty in illness ,social support and depression in patient with cholangiocarcinoma.


.This was a descripitive-correlational cross-sectional study.In this study, the convenience sampling was used. Seventy patients of cholangiocarcinoma was recruited from  gastroenterology general surgery, hepatic-biliary-pancreatic- medicine, hematology and oncology inpatient and outpatient department in one northern medical center.

The structured questionnaires including 「demopraphic data 」,「Mishel’s Uncertainty in Illness Scale –Adult :MUIS-Adult)」,「Medical Outcomes Study Social Support Survey : MOS Social Support Survey」,「Beck’s  Depression Inventory:BDI-II)」and「symptom distress scale for cholangiocarcinoma patient」.The data were analyzed by SPSS for 18.0 in term of descriptive statistics , Univariate logistic regression analysis and Logistic hierarchical regression analysis.


1. Cholangiocarcinoma in patients with depression average score 16.62 points , 55.7% of patients had depression.

2. Cholangiocarcinoma  patients uncertainty in  illness was significantly related to depression, Uncertainty in illness are more prone to more severe depression symptoms

3. Cholangiocarcinoma  patients symptom distress was significantly related to depression, symptom distress  are more prone to more severe depression symptoms

4. Important explanatory factor of cholangiocarcinoma in patients with depression as adisease and symptom distress, uncertainty.When the symptom distress that they have for each 1 score increase in ilness was increased 1.22

time the chance, uncertainty in illness was increased by 1 socre that they have opportunity do depression as 1.66 times.


Results of this study provide clinical staff understand the cholangiocarcinoma  and its influencing factors in patients with depression, Hope this study can be used as medical care of these patients clinical reference, to increase the adaptive capacity of patients, thereby reducing depression  generated.