Methods: Research articles through Medline and PubMed.
Results: Understanding the magnitude and scope of the problem of medication non-adherence is the first step in reaching better adherence rates. The second step is to evaluate the risk factors for each patient for medication adherence/non-adherence. Steps are then taken to prevent non-adherence.
Conclusion: The implications for nurse practitioners include using time with patients to assist them in adherence, building a trusting relationship with patients, and developing protocols for assessing and preventing non-adherence.