Purpose: The purposes of this study are to develop and examine physical activity program, on primary outcomes (cognitive function & IADL), and secondary outcomes (physical fitness, QOL, social support and depression) among community-dwelling elderly adults with MCI.
Methods: We developed a PA stage-matched intervention (SMI) base on the Transtheoretical Model of Change (TMC), literature and our previous findings, then, 81 elderly adults with MCI were recruited in to a 2-group pretest-posttest randomized controlled trial for 6 months and a 6-month follow-up to examine its effectiveness among community-dwelling elderly with MCI. The 24-week SMI consist of three components: (a) the stage-matched counseling strategies base on main constructs derived from the TMC; (b) exercise behavior training: we provided a 24-week, 2 times group-based (8-12 participants with 2 instructors at community centers, 60’ each) and one home-based (with the PA program VCD and manual to bring home, 30’); and (c) telephone counseling each week.
Results: After this 24-week PA SMI, the PA group participants showed significantly better MMSE than those in the comparison group (t=2.585, p=.012); however, Mixed model analysis showed significantly on group effect only (F=8.846; p＝.004). Also, the PA participants demonstrated significantly better mobility (interaction effects F=5.325; p＝.024).
Conclusion: A 24-week PA SMI could improve cognitive and mobility ability among MCI elderly adults. However, more participants and physical activity other non-pharmacological interventions (such as cognitive training) may boost the effects on cognitive function among MCI elderly.