Completeness of Human Papilloma Virus (HPV) Vaccination: A Systematic Review of the Literature

Thursday, 27 July 2017: 2:30 PM

Hee Sun Kang, PhD, RN1
Jennie C. De Gagne, PhD, DNP, RN-BC, CNE, ANEF, FAAN2
Ye Dong Son, MSN1
(1)Red Cross College of Nursing, Chung-Ang University, Seoul, Korea, Republic of (South)
(2)School of Nursing, Duke University, Durham, NC, USA

Purpose:  Human Papilloma Virus (HPV) vaccination is known to be effective for preventing cervical cancer and condyloma. For its maximum effects, it is important not only to initiate HPV vaccination, but also to complete it on time. However, it has been reported that the completeness rate of HPV vaccination is lower than its initiation rate. The aim of this study was to systematically review the intervention studies on HPV vaccination completion.

Methods:  A systematic review of intervention studies examining the completeness of HPV vaccination in women (adolescents and young women) from 2006 to 2016 was conducted. The main outcome assessed was completion rate. We searched the databases ofWeb of Science, PubMed, and Cumulative Index to Nursing and Allied Health Literature, for relevant articles. Reference lists of included articles were also hand-searched. Two reviewers independently completed data extraction and bias assessments using standardized forms. Originally, the possibilities of pooling data were considered, but the data were analyzed narratively because of the heterogeneity of the types of interventions.

Results:  Five studies were identified and reviewed. Intervention strategies were DVD education on HPV and reminder/recall systems using either electronic or non-electronic methods. Electronic reminders were either fixed without options or were preference-based, which allowed parents or women (adolescents or young women) to select one or two options among e-mail, text, automated telephone message, Facebook message, etc. Non-electronic reminders were letter, standard mail, phone call, etc. The rates of HPV vaccination completeness increased with the interventions. However, the completeness rate of HPV vaccination, remaining unsatisfactory, was lower than its initiation rate. The reviewed studies have mainly been conducted in a high income country.

Conclusion:  Educational or reminder interventions on HPV vaccination could contribute to the promotion of HPV vaccination completion. However, this review highlights that more high quality studies are needed to explore the barriers to completion and to identify the best way to promote vaccination completion.