Learning Objective 1: To discuss the trends observed in cardiac pain intensity, state anxiety and pain management during the first 8 hours of an acute coronary syndrome onset.
Learning Objective 2: To explain the evidence pertaining to the potential impact of persistent high anxiety on ACS-related cardiovascular outcomes and incorporate implications within clinical practice.
Aim: We examined the relationship between pain management and cardiac pain intensity and state anxiety for rural ACS patients awaiting diagnostic CATH.
Methods: A prospective, descriptive-correlational repeated-measure design was used to examine the association of cumulative analgesic administration with cardiac pain intensity (numeric rating scale-NRS) and state anxiety (Speilberger State Anxiety Inventory-SAI) via multiple variable linear mixed effects regression models.
Results: The mean age of ACS patients (n=121) was 67.6 ±13, 50% were male, 60% had unstable angina and 40% had Non-ST-Elevated myocardial infarction. During follow up, cardiac pain intensity scores remained in the mild range over 8 hours from 1.1 ± 2.2 to 2.4 ±2.7. State anxiety ranged from 44.0 ±7.2 to 46.2 ±6.6. Cumulative analgesic dose was associated with a reduction in cardiac pain by 1.0 points (NRS, 0-10) (t(108)=-2.5, SE=-0.25, CI (-0.45, -0.06), p=0.013). Analgesic administration was not associated with state anxiety. Through the course of follow up ACS patients reported high anxiety scores indicating a persistent anxious state.
Implications: Despite adequate analgesic administration anxiety scores remained high, leaving patients at risk for increased thrombus formation and lethal dysrhythmias. A larger prognostic study is required in order to determine whether high levels of anxiety for rural patients are predictive of major adverse cardiac events.