Poster Presentation
Thursday, 20 July 2006
10:00 AM - 10:30 AM
Thursday, 20 July 2006
3:00 PM - 3:30 PM
This presentation is part of : Poster Presentations II
The Influence of the Blood Sampling Related Variables on N-K Cell
Dalsook Kim, PhD, RN, Nursing Department, Chungnam National University, Daejeon City, South Korea, Seong Yoon Ahn, MS, Nursing, Kimcheon Science College, Kimcheon, South Korea, and Young-Hee Jeong, RN, BS, Nursing Dept, Chung-Nam National University, Daejeon, South Korea.
Learning Objective #1: understand there is an influence of the blood sampling time on N-K cell.
Learning Objective #2: understand there is an influence of the interval between the time of measurement of the hope level and of the blood sampling on N-K cell.
Background: There’s a paucity of the immune study concerning the timing of the blood sampling in the cancer patients. This has caused contradictory findings in previous studies relating psychosocial variables to immune function or to the development or progression of cancer.
Objectives: To examine whether any difference on the levels of N-K cell among the person groups classified by time of the blood sampling exists or not.
To examine whether any differences on the levels of N-K cell among the person groups classified by the interval between time of measuring hope level and time of blood sampling exist or not.
Method: The study included the 24rectal cancer patients and 25breast cancer patients in the newly diagnosed cancer patients just before treatment for cure. Informed consents were made for all the procedures related to blood sampling and measuring the level of hope, which is regarded as a acute stress here. N-K cell were analyzed with FACS method.     
Results: There was significant difference on the level of the N-K cell among the groups with the mean values of 14.0150(blood sampling in 9:00A.M-noon), 20.1709(in noon-6 P.M), and 9.9766(8.00 P.M.-midnight)(p=.000). Mean plot of sampling time showed there' s a circadian variation. There was significant difference on the level of N-K cell among the groups with the mean values of 15.5308(interval: 5-30min), 10.5593(interval: 31-60min), 9.4200(interval: 61-120min), and 8.3833(interval: more than 120min)(p= .036). There’s a significant relationship between the interval and the level of the N-K cell (p= -.317, p= .026). The mean plot of the interval revealed a sudden decrease at 30min.
Conclusions:  The results would be utilized as the data related to determination of the timing of the blood sampling for the studies relating psychosocial variables to N-k cell in the newly diagnosed cancer patients.          

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