Paper
Wednesday, July 11, 2007
Is polyethylene glycol lavage better than magnesium citrate plus cleansing enema for colonoscopy preparation ?
Yu-Chen Lu, RN, Nursing department, Kaohsiung Chang Gung Memorial Hospital .Kaohsiung Medical center, Kaohsiung, Taiwan
| Learning Objective #1: The learner will be able to provide a simple, safe, rapid, and less discomfortable modality for bowel preparation for patients under going colonoscopy.
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| Learning Objective #2: The learner will be able to encourage high risk patients to complaint the order for the early detection of colorectal cancer such as colonoscopy
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We compare the effectiveness, acceptability, and patient discomfort of polyethylene glycol (PEG) lavage (Klean-PrepÒ) and magnesium citrate plus cleansing enema prior to colonoscopy. Sixty patients without obstructive colonic disease were randomized to receive either standard 2 L of PEG (n=30) or magnesium citrate plus cleansing enema (n=30), prior to colonoscopic evaluation. The study endpoints were the percentage of subjects who had completed the preparation, the tolerance, discomfort and acceptability assessed by a structured questionnaire. Survey data was analyzed by using SPSS 10.0. There was no significant difference in bowel preparation between PEG group and magnesium citrate/cleansing enema group (p=0.084). However, a significantly lower score of discomfort was found in the PEG group compared to the magnesium citrate/cleansing enema group (3.20±0.37 vs. 1.67±0.58, p=0.000). PEG lavage decreases the discomforts for colonoscopy preparation. Our findings may provide a simple, safe, rapid, and less discomfortable modality for bowel preparation to raise consideration for colonoscopy, and furthermore, to increase the early detection and decrease the mortality of colorectal cancer.