Cancer Symptom Distress and Quality of Life in Adolescent Patients with Cancer

Monday, July 11, 2011

Wei-Wen Wu, PhD, RN
Department of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan

Learning Objective 1: The learner will be able to understand the outcomes of cancer symptom distress, quality of life (QoL) and resilience in the adolescent patients with cancer

Learning Objective 2: The learner will be able to understand the relationships among cancer symptom distress, QoL, and resilience.

To describe participants’ cancer symptom distress, QoL and resilience with outcomes of Electronic Self Report Assessment – Cancer Adolescent Form (ESRA-C AF); to explore cancer symptom distress, resilience and QoL scores for various demographic factors; and to determine whether resilience is a mediating variable between cancer symptom distress and QoL, a descriptive, cross-sectional study was conducted. A convenience sample of 40 consecutive adolescent patients aged from 13 to 20 and treated with cancer, could communicate in English, and were component to understand the study information and gave informed consent (18-20 years old) and assent (13-17 years old) were invited to participate in the study held in pediatric Hematology/Oncology and Orthopedics ambulatory setting between November 2008 and January 2009 at a Children hospital in Washington State. The electronic survey tool consisted of valid measures (electronic Minneapolis-Manchester Quality of Life – Adolescent Form (MMQL-AF), Symptom Distress Scale (SDS) and RS (Resilience Scale)) was administered. The result revealed that the physical functioning was the worst outcome reported among the MMQL-AF and fatigue the item most endorsed above threshold in the SDS. Regarding the correlations among MMQL-AF, SDS, and RS scores, there was a significant correlation (r = -.766) between the MMQL-AF and the SDS (p < 0.01), and a significant correlation (r = .558) between the MMQL-AF and the RS (p < 0.01), as well as a significant correlation (r = -.440) between the SDS and the RS (p < 0.01). The result of model testing was that resilience could mediate the effects of cancer symptom distress on QoL. The conclusion was that relieving cancer symptom distress may enhance resilience and enhancing resilience may improve QoL. Planning interventions focusing on managing cancer symptom distress and enhancing resilience may improve adolescent cancer patients’ QoL in this vulnerable population.