This presentation will describe the CIS/simulation learning approaches used within each course. Strategies vary in scope and complexity based on level of the student. For example, sophomore nursing students get early experience with the CIS by documenting assessment and intervention data in simulated focused activities, e.g., providing wound care. Juniors prepare for their simulated post-operative mastectomy patient scenario by reading the history and other relevant patient data within the CIS. During simulation, students look up the simulated patient’s lab values, check orders and document care in “real time”. Personal digital assistants are also used as real time electronic reference tools when delivering care to this virtual patient. Senior students in the High Acuity Course are the most advanced in their use of the CIS in simulation. Students access the CIS remotely and plan the care for their assignment. For seniors, the care to be delivered is more complex and uncertain, thus the need for timely data is more critical to drive decision-making. Regardless of the student level, faculty participating in these simulations are stressing the importance of managing information to drive point of care decisions and application of evidence-based practice.